Mark 7:32-37: "32 And they brought to him a man who was deaf and had a speech impediment, and they begged him to lay his hand on him. 33 And taking him aside from the crowd privately, he put his fingers into his ears, and after spitting touched his tongue. 34 And looking up to heaven, he sighed and said to him, 'Ephphatha,' that is, 'Be opened.' 35 And his ears were opened, his tongue was released, and he spoke plainly. 36 And Jesus charged them to tell no one. But the more he charged them, the more zealously they proclaimed it. 37 And they were astonished beyond measure, saying, 'He has done all things well. He even makes the deaf hear and the mute speak.'"
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While it's obvious that the hymn is based on this passage from Mark 7, there are only a couple elements from the passage that are actually in the hymn text. Part of verse 37 is the basis for the first three lines of the hymn ("O Son of God, in Galilee / You made the deaf to hear, / The mute to speak, the blind to see") and for the first half of the third verse ("The speechless tongue, the lifeless ear / You can restore, O Lord"), and the word ephphatha from verse 34 appears in the second half of the third verse ("Your 'Ephphatha,' O Savior dear, / Can instant help afford").
The line "O bid them cast on You their care" in the second verse bears some resemblance to the first part of Psalm 55:22 ("Cast your burden on the LORD, and he will sustain you") and 1 Peter 5:7 ("casting all your anxieties on him, because he cares for you").



